Observation of radiation sickness and leucocyte count were made in 20 cases of squamous cell carcinoma of the uterine cervix, receiving Cesium deep therapy over,periods of about 40 days at the Dept. of Obst. & Gynec., Han-11 Hospital
In 7 cases of these, urinary excretion of 17-ketosteroids was determined according to the method of Drekter.
The leucocytee count and the determination of urinary excretion of 17-ketosteroids were carried´ out before and during Cesium deep therapy.
Fatigability, anorexia, nausea and vomiting, headache, dizziness, abdominal pain, insomnia, thirst. fever, pollakisuria and diarrhea were considered to be suggestive of radiation sickness. The following results were obtained:
1.) As to the radiation sickness, diarrhea is noticed in 13 cases, fatigability in 11 cases and anorexia in 10 cases, respectively. The highest incidence of these symptoms(60 per cent) is. seen on the tenth day of irradiation.
2.) Leucocytc count is decreased gradually with increasing irradiation dosage of Cesium.
3.) The urinary excretion of 17-ketosteroids begins to increase above the preirradiation levell from the begining of irradiation and reaches its highest level on the tenth day of irradiation, after which a decrease is noted. It becomes lower than preirradiation level from the thirtieth day of irradiation.
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